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Subclinical hypothyroidism hyperprolactinemia: Subclinical Hypothyroidism and Link to Hyperprolactinemia

Researchers believe that this finding explains the causative role of hyperprolactinemia in infertility. Patients with pregnancy, pituitary adenomas, secondary hypothyroidism, hyperthyroidism, comorbid states and drug-induced hyperprolactinemia were excluded.

Bone marker and bone density responses to dopamine agonist therapy in hyperprolactinemic males. Caspian J Intern Med ; Received May 22; Accepted May Sign in to save your search Sign in to your personal account. Thyroid deficiency in the Framingham study.

  • Prevalence and predictors of hyperprolactinemia in subclinical hypothyroidism. Sign in to save your search Sign in to your personal account.

  • Background: Hyperprolactinemia is the most common endocrine disorder in hypothalamic-pituitary axis and has been reported in variable levels in patients with overt primary hypothyroidism. This study aimed to determine the prevalence and predictors of hyperprolactinemia in ScH.

  • They did a cross-sectional study and assessed the prolactin levels of subclinical hypothyroid patients. Request Username Can't sign in?

  • Prevalence of hyperprolactinemia in subclinical hypothyroidism was

MeSH terms

Prolactin is a pituitary hormone that plays an important role in a number of reproductive functions. Subclinical hypothyroidism. Bahar A, et al.

Abstract Background: Hyperprolactinemia is the most common endocrine disorder in hyperprolactinemia axis and has been reported in variable levels in patients with overt primary hypothyroidism. In males, serum estradiol was significantly higher, and testosterone significantly lower in men with ScH and primary hypothyroidism. Prevalence of hyperprolactinemia in subclinical hypothyroidism was These results led to the conclusion that more severe hypothyroidism, as displayed by higher TSH levels, leads to a greater thyrotropin-releasing hormone—mediated prolactin release. Methods: Consecutive patients diagnosed to have normal thyroid function, ScH or overt primary hypothyroidism underwent serum prolactin, gonadotropins, testosterone and estradiol estimation. The mean age of the patients was Regression analysis revealed serum TSH followed by free T 4to be best predictors of serum prolactin in both sexes.

Data guy friend wants me to lose weight hyperprolactinemia in subclinical hypothyroidism ScH is scant and inconsistent. The mean age of the patients was Methods: Consecutive patients diagnosed to have normal thyroid function, ScH or overt primary hypothyroidism underwent serum prolactin, gonadotropins, testosterone and estradiol estimation. Along with this finding, it was revealed that the prevalence of infertility was higher in the presence of hyperprolactinemia than in the presence of normoprolactinemia in patients with subclinical hypothyroidism.

  • The predominant signal is inhibitory, preventing prolactin release and is mediated by dopamine. Forgot password?

  • Keywords: Clinical symptom; Hyperprolactinemia; Subclinical hypothyroidism.

  • Hyperprolactinemia has been reported in subclinical hypothyroidism SCH but results are markedly variable and studies on SCH are very few.

Hyperprolactinemia in association with subclinical hypothyroidism. Hyperprolactinemia with galactorrhea can occur in SCH. Kenneth E. If the address matches an existing account you will receive an email with instructions to reset your password. Philadephia: Wolters Kluver;

Abstract Background: Hyperprolactinemia is the most common endocrine disorder in hypothalamic-pituitary axis and has been reported in variable levels in patients with dubclinical primary hypothyroidism. A cross-sectional study of the relationship between these two disease states was recently published in the Journal of Family Medicine and Primary Care. There was no correlation between the serum TSH and prolactin level. Although further studies are needed to examine the association between hyperprolactinemia and subclinical hypothyroidism, routine evaluation of prolactin serum level may be recommended in patients with subclinical hypothyroidism.

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Results: From initially screened patients, hormonal data from individuals who fulfilled all criteria were analyzed. Substances Testosterone Estradiol Prolactin Thyrotropin. All rights reserved. Methods: In this cross sectional hyperprolatinemia, prolactin levels of subclinical hypothyroid patients were assessed. Thyroid-hormone levels, along with serum prolactin levels, were measured utilizing an electrochemiluminescence assay. Prolactin measurement was performed using chemiluminescent immunoassay. Although further studies are needed to examine the association between hyperprolactinemia and subclinical hypothyroidism, routine evaluation of prolactin serum level may be recommended in patients with subclinical hypothyroidism.

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After one year of follow-up the patient had normal prolactin levels. Volume 13 Issue 10 Oct Philadelphia: Lippincott Williams and Wilkins; Author information Article notes Copyright and License information Disclaimer. Prevalence and predictors of hyperprolactinemia in subclinical hypothyroidism. They evaluated individuals who were either euthyroid or had subclinical or overt hypothyroidism and their correlation with TSH and prolactin. Evaluation of serum prolactin level in patients of subclinical and overt hypothyroidism.

There was no correlation between the serum TSH and prolactin level. Reproduction in whole or in part without permission is prohibited. Data on hyperprolactinemia in subclinical hypothyroidism ScH is scant and inconsistent. Data were collected and analyzed. All rights reserved. Methods: In this cross sectional study, prolactin levels of subclinical hypothyroid patients were assessed.

Introduction

Data on hyperprolactinemia in subclinical hypothyroidism Hyperprolactinemia is scant and inconsistent. Prevalence of hyperprolactinemia in subclinical hypothyroidism was The mean age of the patients was Overall, the most common complaints reported by participants included menstrual irregularities

Hyperprolactinemia has been reported in subclinical hypothyroidism SCH but results are markedly variable and studies on SCH are very few. Thyroid Vol. Thyroid-hormone levels, along with serum prolactin levels, were measured utilizing an electrochemiluminescence assay. The prevalence of hyperprolactinaemia in overt and subclinical hypothyroidism. They did a cross-sectional study and assessed the prolactin levels of subclinical hypothyroid patients.

  • Physical examination showed non-tender, diffuse enlargement of the thyroid gland, which was unchanged over the past one year.

  • Clinical symptom prevalence was not different between patients with and without hyperprolactinemia.

  • Hypothyroid symptoms and the likelihood of overt thyroid failure: A population-based case-control study. All content published within Cureus is intended only for educational, research and reference purposes.

  • In the few hypothyroid patients who have elevated serum prolactin levels, the values become normal when the hypothyroidism is corrected [ 2 ].

  • Thyroid Vol. She had a past medical history of hypertension, latent tuberculosis TB and sciatica.

The mean age of the patients was subclinical hypothyroidism hyperprolactinemia Regression analysis revealed serum TSH followed by free T 4to be best predictors of serum prolactin in hyypothyroidism sexes. Abstract Background: Hyperprolactinemia is the most common endocrine disorder in hypothalamic-pituitary axis and has been reported in variable levels in patients with overt primary hypothyroidism. Overall, the most common complaints reported by participants included menstrual irregularities Results: From initially screened patients, hormonal data from individuals who fulfilled all criteria were analyzed.

In males, serum estradiol was significantly higher, and testosterone significantly lower in men with ScH and subclinical hypothyroidism hyperprolactinemia hypothyroidism. Few studies have examined the prevalence of hyperprolactinemia in subclinical hypothyroidism. Clinical symptom prevalence was not different between patients with and without hyperprolactinemia. This study aimed to determine the prevalence and predictors of hyperprolactinemia in ScH.

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Isoniazid associated, painful, bilateral gynaecomastia. Sign in to download free article PDFs Sign in to access your subscriptions Sign in to your personal account. Published online May Prolactin response to thyrotropin releasing hormone in normal subjects. Prolactin is a peptide hormone produced by lactotroph cells of the anterior pituitary gland and is primarily associated with lactation.

  • Endocr J.

  • Data were collected and analyzed.

  • They did the study to investigate sexual dysfunction in patients with clinical hypothyroidism and SCH. The spectrum of thyroid disease in a community: The Whickham survey.

Substances Testosterone Estradiol Prolactin Thyrotropin. Additionally, there was a positive correlation between serum TSH and prolactin levels. Hyperprolactonemia believe that this finding explains the causative role of hyperprolactinemia in infertility. Ninty-eight patients 91 females 7 males had high prolactin. There was no correlation between the serum TSH and prolactin level. The mean age of patients was A cross-sectional study of the relationship between these two disease states was recently published in the Journal of Family Medicine and Primary Care.

Physiologic causes include pregnancy, nipple stimulation, and stress. This hyperprolactinemia has been cited by. Levothyroxine sodium 0. Arch Intern Med ; Physical examination showed non-tender, diffuse enlargement of the thyroid gland, which was unchanged over the past one year. Human Ethics Consent was obtained by all participants in this study.

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Published by Elsevier B. Conclusion: This study showed that prevalence of subclinical hypothyroidism hyperprolactinemia in subclinical hypothyroidism is notable and this disorder is more common in female subclinical hypothyroidism than the men. In males, serum estradiol was significantly higher, and testosterone significantly lower in men with ScH and primary hypothyroidism.

Introduction Hyperprolactinemia is common in primary hypothyroidism, but, subclinical hypothyroidism hyperprolactinemia our knowledge, marked elevation of serum prolactin in subclinical hypothyroidism SCH has not been commonly reported Sachmechi I, Reich D, Bhatti H, Kim P: Hyperprolactinemia with galactorrhea due to subclinical hypothyroidism, abstract. Evaluation of serum prolactin level in patients of subclinical and overt hypothyroidism. Published online May J Sex Med. In conclusion, they explained that SCH was observed in women with hyperprolactinaemia and the ratio of proportions between hyperprolactinemia and hypothyroidism was ; in simple words, in every seven women with hyperprolactinemia, one had hypothyroidism. Olive, MC ; James V. Please review our privacy policy.

Materials and Me Prevalence of infertility was significantly higher with presence of hyperprolactinemia than normoprolactinemia in subclinical hypothyroid patients. Thyroid hormone replacement for subclinical hypothyroidism. Returning user.

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J Endocrinol ; Sitemap What's New Feedback Disclaimer. Her last menstrual period was three weeks prior to her presentation.

There was no correlation between the serum TSH and prolactin level. The occurrence of hyperprolactinemia females:males was highest in aubclinical subclinical hypothyroidism hyperprolactinemia We decided to determine the prevalence of hyperprolactinemia and clinical related symptoms in subclinical hypothyroidism patients. Patients with pregnancy, pituitary adenomas, secondary hypothyroidism, hyperthyroidism, comorbid states and drug-induced hyperprolactinemia were excluded. Regression analysis revealed serum TSH followed by free T 4to be best predictors of serum prolactin in both sexes.

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Sign in to make a comment Sign in to your personal account. Philadephia: Wolters Kluver; Drug hyperprrolactinemia diseases, endocrinology. Subclinical hypothyroidism in infertile women: The importance of continuous monitoring and the role of the thyrotropin-releasing hormone stimulation test. Estimation of serum prolactin levels and determination of prevalence of hyperprolactinemia in newly diagnosed cases of subclinical hypothyroidism.

Thyroid hormone replacement for subclinical hypothyroidism. Thyroid deficiency in the Framingham study. Results of visual field testing were normal, and a computed tomographic scan of the pituitary gland revealed no evidence of a macroadenoma. Based on blinded TSH monitoring, physiologic levothyroxine replacement She had negative urine pregnancy test.

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Conclusion: This study showed that prevalence of hyperprolactinemia in subclinical hypothyroidism is notable and this disorder is more common in female subclinical hypothyroidism than the men. This cross-sectional study included patients in India with subclinical hypothyroidism. Significant positive correlation between TSH and prolactin was noted in ScH and primary hypothyroidism.

Subclinical hypothyroidism hyperprolactinemia S. Behavior in dogs with spontaneous hypothyroidism during treatment with levothyroxine. How to cite this article: Sirohi T, Singh H. New Password. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Sign in subclknical access your subscriptions Sign in to your personal account. A year-old woman presenting with carpal tunnel syndrome was found to have a minimally elevated level of thyrotropin with a normal level of thyroxine. Prolactin is a pituitary hormone that plays an important role in a number of reproductive functions. Human Ethics Consent was obtained by all participants in this study. Forgot password? Hyperprolactinemia and pregnancy. If the address matches an existing account you will receive an email with instructions to reset your password.

October Prevalence and predictors hypotyyroidism hyperprolactinemia in subclinical hypothyroidism. Evaluation of serum prolactin level in patients of subclinical and overt hypothyroidism. Discussion Prolactin is a peptide hormone produced by lactotroph cells of the anterior pituitary gland and is primarily associated with lactation. Low thyroid levels associated with subclinical hypothyroidism, in combination with raised prolactin levels, have been implicated in ovulatory dysfunction that leads to infertility.

Sign in to access your subclinical hypothyroidism hyperprolactinemia Sign in to your personal account. Prolactin dysregulation in women with subclinical hypothyroidism: Effect of levothyroxine replacement therapy. Hekimosy Z, et al. Asa SL, Ezzat S. None of the patients reported menstrual disturbances, infertility, or galactorrhea.

Prolactin levels decreased to normal in all hypotthyroidism after thyroid functions normalized with levothyroxine treatment. This cross-sectional study included patients in India with subclinical hypothyroidism. Year : Volume : 7 Issue : 6 Page : Arch Intern Med. Prolactin is under dual regulation by hypothalamic hormones delivered through the hypothalamic-pituitary circulation. If the address matches an existing account you will receive an email with instructions to retrieve your username.

National Center for Biotechnology InformationU. A year-old woman presenting hypthyroidism carpal tunnel syndrome was found to have a minimally elevated level of thyrotropin with a normal level of thyroxine. Close follow-up of serum prolactin levels should be done before, during, and after treatment in order to avoid unnecessary imaging such as MRI of the brain. In conclusion, they explained that SCH was observed in women with hyperprolactinaemia and the ratio of proportions between hyperprolactinemia and hypothyroidism was ; in simple words, in every seven women with hyperprolactinemia, one had hypothyroidism.

Patients with pregnancy, pituitary adenomas, secondary hypothyroidism, hyperthyroidism, comorbid states and drug-induced hyperprolactinemia were excluded. Additionally, patients with hyperprolactinemia Jyperprolactinemia values 7. Background: Hyperprolactinemia is the most common endocrine disorder in hypothalamic-pituitary axis and has been reported in variable levels in patients with overt primary hypothyroidism. All rights reserved. This study aimed to determine the prevalence and predictors of hyperprolactinemia in ScH.

Overall, the most common complaints reported by participants included menstrual irregularities Published by Elsevier B. Methods: Consecutive patients diagnosed to have normal thyroid function, ScH or overt primary hypothyroidism underwent serum prolactin, gonadotropins, testosterone and estradiol estimation. Few studies have examined the prevalence of hyperprolactinemia in subclinical hypothyroidism. Additionally, there was a positive correlation between serum TSH and prolactin levels. Substances Testosterone Estradiol Prolactin Thyrotropin.

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Although further studies are needed to examine the association between hyperprolactinemia and subclinical hypothyroidism, routine evaluation of prolactin serum level may be recommended in subclinical hypothyroidism hyperprolactinemia with subclinical hypothyroidism. Keywords: Clinical symptom; Hyperprolactinemia; Subclinical hypothyroidism. This cross-sectional study included patients in India with subclinical hypothyroidism. Few studies have examined the prevalence of hyperprolactinemia in subclinical hypothyroidism. A cross-sectional study of the relationship between these two disease states was recently published in the Journal of Family Medicine and Primary Care. We decided to determine the prevalence of hyperprolactinemia and clinical related symptoms in subclinical hypothyroidism patients.

In patients with hypothyroidism, an subclinixal in prolactin is due to compensatory increase in the discharge of central hypothalamic TRH as a result of low thyroxine [ 1 ]. The importance of thyroid microsomal antibodies in the development of elevated serum TSH in middle-aged women: Associations with serum lipids. Prolactin dysregulation in women with subclinical hypothyroidism: effect of levothyroxine replacement therapy. Subclinical thyroid disease: Clinical applications.

All rights reserved. Results: From initially screened patients, hormonal data from individuals who fulfilled all criteria were analyzed. Additionally, there was a positive correlation between serum TSH and prolactin levels.

Conclusion: This study sucblinical that prevalence of hyperprolactinemia in subclinical hypothyroidism is notable and this disorder is more common in female subclinical hypothyroidism than the men. Significant positive correlation between TSH and prolactin was noted in ScH and primary hypothyroidism. Data on hyperprolactinemia in subclinical hypothyroidism ScH is scant and inconsistent. The mean age of patients was

Thyroid-hormone levels, along with serum prolactin levels, were measured utilizing an electrochemiluminescence assay. Results and Disc Pathologic subclinical hypothyroidism hyperprolactinemia include lactotroph adenomas, other hypothalamic and pituitary disorders. None of the patients reported menstrual disturbances, infertility, or galactorrhea. Password Changed Successfully Your password has been changed. She denied the use of tobacco, marijuana, alcohol, illicit drugs, or over the counter medicines.

Keywords: primary hypothyroidism, subclinical hypothyroidism, levothyroxine, hyperprolactinemia, galactorrhea. Yyperprolactinemia levels, along with serum prolactin levels, were measured utilizing an electrochemiluminescence assay. Volume 13 Issue 10 Oct After looking at her thyroid function tests, prolactin level, and other respective tests, a diagnosis of subclinical hypothyroidism with hyperprolactinemia was made. Sign in to save your search Sign in to your personal account.

  • Get free access to newly published articles.

  • Methods: In this cross sectional study, prolactin levels of subclinical hypothyroid patients were assessed. Results: From initially screened patients, hormonal data from individuals who fulfilled all criteria were analyzed.

  • Thyrotropin releasing hormone stimulation testing revealed hyperresponsiveness consistent with primary hypothyroidism.

Forgot your username? Sign in to access your subscriptions Sign in to your personal account. Marked hyperprolactinemia in subclinical hypothyroidism. Forgot password?

The occurrence of subflinical females:males was highest in primary hypothyroidism Reproduction in whole or in part without permission is prohibited. Along with this finding, it was revealed that the prevalence of infertility was higher in the presence of hyperprolactinemia than in the presence of normoprolactinemia in patients with subclinical hypothyroidism. Ninty-eight patients 91 females 7 males had high prolactin.

Additionally, patients with higher TSH values 7. All rights reserved. Overall, the most common complaints reported by participants included menstrual irregularities

All rights lose. Regression analysis revealed serum TSH followed by free T 4to be best predictors of serum prolactin in both sexes. Although further studies are needed to examine the association between hyperprolactinemia and subclinical hypothyroidism, routine evaluation of prolactin serum level may be recommended in patients with subclinical hypothyroidism. Background: Hyperprolactinemia is the most common endocrine disorder in hypothalamic-pituitary axis and has been reported in variable levels in patients with overt primary hypothyroidism.

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Enter your email address below and we will send you the reset instructions. Am Fam Physician ; Merih Guglielmetti Search for more papers by this author. They studied infertile Nigerian women with hyperprolactinemia with subclinical hypothyroidism. Prevalence and predictors of hyperprolactinemia in subclinical hypothyroidism. Prolactin response to thyrotropin releasing hormone in normal subjects. Tolino A, et al.

Hyperprolactinemia and pregnancy. Arch Intern Med. Prolactin levels decreased to normal in all patients after thyroid functions normalized with levothyroxine treatment. Hyperprolactinemia is common in primary hypothyroidism, but, to our knowledge, marked elevation of serum prolactin in subclinical hypothyroidism SCH has not been commonly reported Sachmechi I, Reich D, Bhatti H, Kim P: Hyperprolactinemia with galactorrhea due to subclinical hypothyroidism, abstract.

The mean prolactin levels were significantly higher in subclinical hypothyroidism hyperprolactinemia hypothyroidism The authors have declared that no competing interests exist. Diagnosis and management of hyperprolactinemia. Endocrinol Metab Clin North Am ;, vii. Tolino A, et al. Sign in to customize your interests Sign in to your personal account.

The mean age of the patients was In subclunical, serum estradiol was significantly higher, and testosterone significantly lower in men with ScH and primary hypothyroidism. Data were collected and analyzed. Results: From initially screened patients, hormonal data from individuals who fulfilled all criteria were analyzed. This cross-sectional study included patients in India with subclinical hypothyroidism.

Published by Elsevier B. The mean age of patients was Keywords: Hyperprolactinemia; Prolactin; Subclinical hypothyroidism; Thyroid stimulating hormone. This cross-sectional study included patients in India with subclinical hypothyroidism. Thyroid-hormone levels, along with serum prolactin levels, were measured utilizing an electrochemiluminescence assay. Clinical symptom prevalence was not different between patients with and without hyperprolactinemia.

Prevalence subcliincal hyperprolactinemia in subclinical hypothyroidism was Few studies have examined the prevalence of hyperprolactinemia in subclinical hypothyroidism. The occurrence of hyperprolactinemia females:males was highest in primary hypothyroidism In females, testosterone was lowest in patients with primary hypothyroidism. These results led to the conclusion that more severe hypothyroidism, as displayed by higher TSH levels, leads to a greater thyrotropin-releasing hormone—mediated prolactin release. Ninty-eight patients 91 females 7 males had high prolactin. Clinical symptom prevalence was not different between patients with and without hyperprolactinemia.

These results led to lose weight conclusion that more severe hypothyroidism, as displayed by higher TSH levels, leads to a greater thyrotropin-releasing hormone—mediated prolactin release. Data were collected and analyzed. Prolactin measurement was performed using chemiluminescent immunoassay. Keywords: Clinical symptom; Hyperprolactinemia; Subclinical hypothyroidism.

These results led to the conclusion that more severe hypothyroidism, as displayed by higher TSH levels, leads to a greater thyrotropin-releasing hormone—mediated prolactin release. Additionally, patients with higher TSH values 7. In males, serum estradiol was significantly higher, and testosterone significantly lower in men with ScH and primary hypothyroidism. Published by Elsevier B.

  • Authors point out correlation between subclinical hypothyroidism-hyperprolactinemia and sterilty.

  • The mean age of patients was

  • Fritz MA, Speroff L. Other causes include idiopathic hyperprolactinemia, hypothyroidism, estrogen administration, chronic renal failure, and macroprolactinemia.

  • All rights reserved. Additionally, there was a positive correlation between serum TSH and prolactin levels.

  • Conclusion: This study showed that prevalence of hyperprolactinemia in subclinical hypothyroidism is notable and this disorder is more common in female subclinical hypothyroidism than the men. Methods: Consecutive patients diagnosed to have normal thyroid function, ScH or overt primary hypothyroidism underwent serum prolactin, gonadotropins, testosterone and estradiol estimation.

This study aimed to determine the prevalence and predictors of hyperprolactinemia in ScH. The mean age of the patients was In males, serum estradiol was significantly higher, and testosterone significantly lower in men with ScH and primary hypothyroidism. These results led to the conclusion that more severe hypothyroidism, as displayed by higher TSH levels, leads to a greater thyrotropin-releasing hormone—mediated prolactin release. There was no correlation between the serum TSH and prolactin level.

Hyperprolactinemia can result from many causes, including hypothyroidism and pituitary disorders as well as hpyothyroidism use. Endocrinology ; Am Fam Physician ; The infertile couple. Additionally, there was a positive correlation between serum TSH and prolactin levels. Sign in to download free article PDFs Sign in to access your subscriptions Sign in to your personal account.

If the address matches an existing account you will receive an email with instructions to reset uyperprolactinemia password. Mirjam Christ-Crain Search for more papers by this author. Hyperprolactinemia with galactorrhea can occur in SCH. In conclusion, they explained that SCH was observed in women with hyperprolactinaemia and the ratio of proportions between hyperprolactinemia and hypothyroidism was ; in simple words, in every seven women with hyperprolactinemia, one had hypothyroidism. Support Center Support Center.

Based on this double-blinded, placebo-controlled study we demonstrate that in subclinical hypothyroidism PRL regulation is subclinical hypothyroidism hyperprolactinemia with elevated basal and stimulated PRL levels, and that physiologic levothyroxine treatment restores PRL concentrations. The incidence of thyroid disorders in community. They did an observational study to determine the prevalence of hyperprolactinemia in patients with newly diagnosed subclinical and overt hypothyroidism and investigated the change in PRL levels with levothyroxine treatment. Get free access to newly published articles. Prolactin is a peptide hormone produced by lactotroph cells of the anterior pituitary gland and is primarily associated with lactation.

Thyroid-hormone levels, along with serum prolactin subclinical hypothyroidism hyperprolactinemia, were measured utilizing hyperprolactiemia electrochemiluminescence assay. In such cases, treatment of SCH with levothyroxine will normalize the prolactin level. Hyperprolactinemia in association with subclinical hypothyroidism. The mean age of patients was Peter Huber Search for more papers by this author. Published online May

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