Obesity

Hypothalamic obesity definition by cdc: Obesity: Definition, Comorbidities, Causes, and Burden

Moreover, 'simple' obesity is associated with polymorphisms in several genes involved in hypothalamic weight-regulating pathways.

The goal of treatment in general is to promote weight loss and control hunger. A pooled analysis of 20 studies reported that heart disease was the most common underlying cause of death in patients with class Boesity obesity BMI Other studies have compared obese and non-obese people for variation in genes that could influence behaviors such as a drive to overeat, or a tendency to be sedentary or metabolism such as a diminished capacity to use dietary fats as fuel, or an increased tendency to store body fat. Diabetes Res Clin Pract. Global, regional, and national prevalence of overweight and obesity in children and adults during a systematic analysis for the Global Burden of Disease Study

  • How Prevalent Is the Problem?

  • Cause Cause. The long-term outlook for people with hypothalamic obesity depends on the cause of the condition and how well weight can be managed.

  • At the greatest risk for obesity are Hispanics and non-Hispanic black women

  • Severe obesity can lead to complications such as diabetes, heart disease, and stroke.

Obesity defined as a chronic disease by leading medical associations

Serum immu-noreactive-leptin concentrations in normal-weight and obese humans. Leptin resistance and obesity are possibly heritable traits. The State of Obesity. In another report, racial segregation in metropolitan areas was not associated with obesity among men; however, segregation did appear to affect obesity rates among some women. Pearce EN.

Worldwide, the prevalence rate for being overweight or obese between and increased Investigators examined the association between those loci and BMI, waist circumference, weight, and height, as well as the predictive value for obesity risk. Drug therapy has limited effectiveness, particularly in children. Participants taking beta-blockers lost a mean 0. Children with obesity were absent from school significantly more Here, you'll learn about some of the most important aspects of managing your child's condition. Genes give the body instructions for responding to changes in its environment.

Li and colleagues reported that 12 obesity-susceptible loci have been identified. Public Health Rep. A list of causes of obesity can be found in the Table. Tips for the Undiagnosed.

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Satisfactory therapy is currently unavailable. Linking to a non-federal website does not constitute an endorsement definifion CDC or any of its employees of the sponsors or the information and products presented on the website. It is conceivable that a subgroup of patients with 'simple obesity' also have HyOb. Tips for Finding Financial Aid.

Consumption patterns, urban development, and lifestyle habits influence the prevalence hypotgalamic obesity. Caring for Your Patient with a Rare Disease. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Expert Opin Drug Saf. Econ Hum Biol. Here, you'll learn about some of the most important aspects of managing your child's condition.

HyOb complicates disorders related to the hypothalamus, including those that cause structural damage to the hypothalamic obesity definition by cdc, pituitary macroadenoma with suprasellar extension, glioma, meningioma, teratoma, germ cell tumors, radiotherapy, Prader-Willi syndrome, and mutations in leptin, leptin receptor, POMC, MC4R and CART hyporhalamic. Association between general and central adiposity in childhood, and change in these, with cardiovascular risk factors in adolescence: prospective cohort study. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Share this content:. Help with Travel Costs. Relation of body mass index and skinfold thicknesses to cardiovascular disease risk factors in children: the Bogalusa Heart Study. Note: For individuals, BMI is screening tool, but it does not diagnose body fatness or health.

Adult Body Mass Index

Finding Funding Opportunities. Furthermore, BMI appears to be strongly correlated with various adverse health outcomes consistent with these more direct measures of body fatness 4,5,6,7,8,9. Obes Rev. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.

  • Additionally, patients who are obese have an increased risk of cancer.

  • Publication types Review.

  • Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5.

Therefore, genetics appear to determine who will become obese, and the environment appears to determine the extent of obesity. Valproic acid, carbamazepine, and gabapentin are antiepileptic medications that are associated with weight gain. Body fatness and markers of thyroid function among US men and women. Eur Thyroid J. The most common cause is related to a rare non-cancerous tumor called a craniopharyngioma.

However, polyphagia and hypoyhalamic gain complicate other disorders related to the hypothalamus, including those that cause structural damage to the hypothalamus like tumours, trauma, radiotherapy; genetic disorders such as Prader-Willi syndrome; side effects of psychotropic drugs; and mutations in several genes involved in hypothalamic satiety signalling. Symptoms Symptoms. Minus Related Pages. Caring for Your Patient with a Rare Disease.

Facebook Twitter LinkedIn Syndicate. Any explanation of the obesity epidemic has to consider both genetics and the environment. Body fatness and markers of thyroid function among US men and women.

Links with this icon defjnition that you are leaving the CDC website. Other mechanisms by which the brain regulates adipose tissue and beta cells of the pancreas include the sympathetic nervous system, vagally mediated hyperinsulinemia and the endocrine system, namely growth hormone, thyroid-stimulating hormone and the hypothalamo-pituitary-adrenal axis. Substances Hormones. Other Names:.

Do you know of a review article? Tips for Finding Financial Aid. Other hypothalamic obesity definition by cdc for hypothalamic obesity include other rare tumors, head trauma, swelling in the brain and being born with a brain malformation. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them. Finding Funding Opportunities. Teaching Resources. We review the studies evaluating possible treatment strategies, including sympathomimetics, somatostatin analogues, triiodothyronine, sibutramine, and surgery.

  • Researchers are still in the process of integrating basic science data with clinical research and learning how to apply the results to patient care. J Clin Endocrinol Metab.

  • How to Find a Disease Specialist. Top of Page.

  • Guaraldi F, Salvatori R.

  • Cancer Additionally, patients who are obese have an increased risk of cancer. Investigators examined the association between those loci and BMI, waist circumference, weight, and height, as well as the predictive value for obesity risk.

  • Adult Obesity Statistics. J Adolesc Health.

Associations between cdc, depression, antidepressant medication, obe-sity, and weight gain among Canadian women. Guidelines for obewity treatment of hypothyroidism: prepared by the American thyroid association task force on thyroid hormone replacement. Physiological factor in obesity. For example, the addition of noradrenergic and specific sero-tonergic antidepressants NaSSAs to selective serotonin reuptake inhibitors SSRIs is associated with a greater incidence of weight gain than SSRI therapy alone. GLP stimu-lates insulin release and inhibits glucagon release in a glucose-dependent manner. Address correspondence to: caroline.

It is recommended that adults engage in at least minutes of moderate-intensity physical activity a week. Body fat in identical twins reared apart: roles for genes and environment. Diabetes Care. Any explanation of the obesity epidemic has to consider both genetics and the environment.

The regulation of food intake is managed by neural and hormonal signals between the gut and central nervous system CNS. Learn about these diabetic neuropathies: peripheral, autonomic, proximal, and focal neuropathies. Children with obesity were absent from school significantly more Public Health Rep. Leptin resistance and obesity are possibly heritable traits.

  • Always consult your doctor about your medical conditions. Regionally, the South had the highest prevalence

  • Caring for Your Patient with a Rare Disease. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.

  • Ghrelin is a potent orexigenic hormone that stimulates food intake.

Cost Containment and Consequences obesity Prevention. Prognosis Prognosis. Dietary energy density in relation to subsequent changes of weight and waist circumfer-ence in European men and women. Beta-blockers, which are used for migraine and myocardial infarction prophylaxis and for the management of hypertension and heart failure, have also been associated with a mean weight gain of 1. A higher BMI in the late-teen years was associated with a lower level of accumulated education, and data from the National Longitudinal Survey of Youth found that a 1-unit increase in BMI is directly associated with 1.

These studies have identified variants hypothalamc several genes that may contribute to obesity by increasing hunger and food intake. A Growing Problem. Obesity: Definition, Comorbidities, Causes, and Burden. Many treatments for T2D are associated with weight gain, with the potential of patients gaining up to 10 kg within 6 months after the start of treatment.

Tips for the Undiagnosed. References References. Inheritance Inheritance. Finding Funding Opportunities. Do you know of an organization?

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Although no correlation has been found between obesity and education in men, women with college degrees are less likely to have obesity than those with less education. Do you know of a review article? References References.

However, polyphagia and weight gain complicate other disorders related to the hypothalamus, including those that cause structural damage to the hypothalamus like tumours, trauma, radiotherapy; genetic disorders such as Prader-Willi syndrome; side effects of psychotropic drugs; and mutations in several genes involved in hypothalamic satiety signalling. We remove all identifying information when posting a question to protect your privacy. Cancel Continue. Orexigenic and anorexigenic hypothalamic centers hyperphagia when impaired play a central role, connecting to adipose tissue by means of an intricate efferent and afferent signals circuit. Association between general and central adiposity in childhood, and change in these, with cardiovascular risk factors in adolescence: prospective cohort study.

  • The mean BMI of the pop-ulation was

  • References 1 Garrow, J. Help with Travel Costs.

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  • Treatment Treatment.

The paradigm shift from thinking of obesity as a character flaw to an understanding that it is a disease is monumental. Use of antipsychotics in the treatment of depres-sive disorders. How to Find a Disease Specialist. Obesity is also a risk factor for major depressive disorder MDD.

We remove all identifying information when posting a question to protect your privacy. Statistics Statistics. Moreover, 'simple' obesity is associated with polymorphisms in several genes involved in hypothalamic weight-regulating pathways. Comparison of body fatness measurements by BMI and skinfolds vs dual energy X-ray absorptiometry and their relation to cardiovascular risk factors in adolescents. Severe obesity can lead to complications such as diabetes, heart disease, and stroke. BMI does not measure body fat directly, but BMI is moderately correlated with more direct measures of body fat obtained from skinfold thickness measurements, bioelectrical impedance, underwater weighing, dual energy x-ray absorptiometry DXA and other methods 1,2,3.

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Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. Expert Opin Drug Saf. Public Health Rep. Genetic changes in human populations occur too slowly to be responsible for the obesity epidemic.

Skip directly to site content Skip directly to page options Skip directly to A-Z link. Section Navigation. Patient Guide to Diabetic Neuropathy Several types of neuropathy nerve damage are caused by diabetes. Cancel Continue. Additionally, patients who are obese have an increased risk of cancer. Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5.

Beta-blockers, which are used for migraine and myocardial infarction prophylaxis and for the management of hypertension and heart failure, have also been associated with a hypothalamic obesity definition by cdc weight gain of 1. The most common cause is related to a rare non-cancerous tumor called a craniopharyngioma. Over the last years, because of technological advances in food processing, the types of foods consumed have changed. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of US adults. A review of the prevalence and economic consequences of obesity is provided. Arch Intern Med.

Body cdx and markers of thyroid function among US men and women. Obes Rev. Guidelines for the treatment of hypothyroidism: prepared by the American thyroid association task force on thyroid hormone replacement. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them. Several medication classes have been associated with weight gain, including antidepressants, atypical antipsychotics, antiepileptic drugs, and beta-blockers.

Publication types

Haliloglu B, Bereket A. The State of Obesity. May ; 28 Other symptoms can include attention deficit hyperactivity disorder ADHDseizuresand psychiatric conditions. Handb Exp Pharmacol.

Links with this icon bypothalamic that you are leaving the CDC website. CDC is not responsible for Section compliance accessibility on other federal or private website. Thus, understanding HyOb may enhance our understanding of 'simple' obesity. We want to hear from you. Facebook Twitter LinkedIn Syndicate. The long-term outlook for people with hypothalamic obesity depends on the cause of the condition and how well weight can be managed. Hypothalamic obesity is usually an acquired condition and is not inherited in families.

CDC is not definition for Section compliance accessibility hypothalamc other federal or private website. Prader-Willi syndrome also shares symptoms with hypothalamic obesity, but it is not generally inherited in families. National Institutes of Health. HyOb, regardless of its aetiology, is a result of impairment in hypothalamic regulatory centres of body weight and energy expenditure. Moreover, 'simple' obesity is associated with polymorphisms in several genes involved in hypothalamic weight-regulating pathways. Testing for specific hormone levels can also help with diagnosis and guide treatment. If you have questions about your BMI, talk with your health care provider.

Although no correlation has been found between obesity and education in men, women with college definition cdc are less likely to have obesity than those with less education. The in-depth resources contain medical and scientific language that may be hard to understand. S n www. Body mass index BMIwhich is weight in kilograms divided by height in meters squared, is used to iden-tify obesity.

They can direct you to research, resources, and services. S n www. Li and colleagues reported that 12 obesity-susceptible loci have been identified. Diabetes Res Clin Pract. However, the alleles combined had limited predictive value for obesity risk.

Learn More Learn More. References 1 Garrow, J. If you have questions about your BMI, talk with your health care provider. Body fat throughout childhood in healthy Danish children: agreement of BMI, waist circumference, skinfolds with dual X-ray absorptiometry. Sept ; 13 9 Substances Psychotropic Drugs. Hypothalamic obesity in children: pathophysiology to clinical management.

You can help advance rare disease research! Craniopharyngiomasthe most common cause of this condition, are very rare and occur in about 1. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Corticotropin-releasing hormone, adrenocorticotropic hormone glucocorticoids and the 11beta-HSD-1 shuttle regulate lipolysis both directly and indirectly. Help with Travel Costs.

We remove all identifying information when posting a question to protect your privacy. BMI does not measure body fat directly, but BMI is moderately correlated with more direct measures of body fat obtained from skinfold thickness measurements, bioelectrical impedance, underwater weighing, dual energy x-ray absorptiometry DXA and other methods 1,2,3. There are a few rare genetic inherited conditions that include the symptoms of hypothalamic obesity such as Bardet-Biedl syndrome and leptin deficiency. Symptoms Symptoms. What's this? Association between general and central adiposity in childhood, and change in these, with cardiovascular risk factors in adolescence: prospective cohort study.

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Intrapair correlations for BMI of identical cdc reared apart were 0. Behavior Genetics. Inclusion on this list is not an endorsement by GARD. Hopefully, this will motivate healthcare professionals to be proactive and intervene sooner when individuals are identified at risk or meet the definition of obesity. Use of antipsychotics in the treatment of depres-sive disorders. A study of monozygotic and dizygotic twins examined the heritability estimates for fat measures and found that these measures were about the same for both sexes, although slightly higher in men.

Obesity is associated with longterm negative economic consequences. There is not one specific treatment for hypothalamic deefinition. J Nutr. Body mass index and risk of rheumatoid arthritis: a meta-analysis of observational stud-ies. The influence on population weight gain and obesity of the macronu-trient composition and energy density of the food supply. J Clin Res Pediatr Endocrinol. Shanghai Arch Psychiatry.

Body fat throughout childhood in healthy Danish children: agreement of BMI, waist circumference, skinfolds with dual X-ray absorptiometry. The goal of treatment in general is to promote weight loss and control hunger. Prognosis Prognosis.

The hypothalamus regulates body weight by obesity balancing the intake of food, energy expenditure and body fat tissue. To receive email updates about this topic, enter your email address. This review will claim that HyOb is a far wider phenomenon than hitherto understood by the narrow definition of post-surgical weight gain. Skip directly to site content Skip directly to page options Skip directly to A-Z link.

READ TOO: Obese Woman Crushes Children S Books

Association between general and central adiposity in childhood, and change in these, with cardiovascular risk factors in adolescence: prospective cohort study. Facebook Twitter LinkedIn Syndicate. Other mechanisms by which the brain regulates adipose tissue and beta cells of the pancreas include the sympathetic nervous system, vagally mediated hyperinsulinemia and the endocrine system, namely growth hormone, thyroid-stimulating hormone and the hypothalamo-pituitary-adrenal axis. The diagnosis of hypothalamic obesity is made based on the symptoms which include a sudden onset of excessive hunger and weight gain after trauma or brain surgery. J Pediatr Endocrin Metab. Diagnosis Diagnosis. Links with this icon indicate that you are leaving the CDC website.

Comparison of bioelectrical impedance and BMI in predicting obesity-related medical conditions. Help with Travel Costs. Diagnosis Diagnosis. Inheritance Inheritance. Top of Page.

If you do not want your question posted, please let us know. Minus Related Pages. All the above mechanisms may be impaired in HyOb. Caring for Your Patient with a Rare Disease. Support for Patients and Families.

The condition definitikn be the result of disease or pharmacologic treatment. Questions sent to GARD may be posted here if the information could be helpful to others. Specific classes of antidepressants are associated with greater weight gain than others. Recent advances in understanding leptin signaling and leptin resistance. A BMI of 25 to

Organizations Supporting this Disease. Tips for Finding Financial Aid. Other causes for hypothalamic obesity include other rare tumors, head trauma, swelling in the brain and being born with a brain malformation. What's this? Substances Psychotropic Drugs.

Share this content:. If obesity could be addressed early in life, it could have a substantial impact on healthcare costs. The paradigm shift from thinking of obesity as a character flaw to an understanding that it is a disease is monumental. Visit the website to explore the biology of this condition. Most people with this condition are treated with a combination of gastric surgery, medications, and nutritional and lifestyle counseling. About AJMC.

Hypothalamkc can direct you to research, resources, and services. Individual variation is considerable. Weight that is higher than what is considered healthy for a given height is described as overweight or obesity. Tips for the Undiagnosed. The long-term outlook for people with hypothalamic obesity depends on the cause of the condition and how well weight can be managed.

National Institutes of Health. Prognosis Prognosis. Summary Summary. Substances Hormones. Comparison of body fatness measurements by BMI and skinfolds vs dual energy X-ray absorptiometry and their relation to cardiovascular risk factors in adolescents.

  • Prevention and management of obesity for chil-dren and adolescents. Potential causes and comorbidities associated with obesity are also discussed.

  • It will emphasize the similarity in clinical characteristics and therapeutic approaches for HyOb, as well as its mechanisms. How to Find a Disease Specialist.

  • Factors associated with sugar-sweetened beverage intake among United States high school students.

  • Publication types Review.

  • Hypothalamic obesity is usually an acquired condition and is not inherited in families.

Treatment Treatment. Polypharmacy, either adding a hypothalamic obesity definition by cdc antidepressant or an atypical antipsychotic, may become necessary for the management of MDD. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. Foods with decreased fiber and increased fat, simple sugar, salt, and increased calories are more readily available, and they are typically cheaper than healthier alternatives. These resources provide more information about this condition or associated symptoms. The most common cause is related to a rare non-cancerous tumor called a craniopharyngioma. Cancer Additionally, patients who are obese have an increased risk of cancer.

HyOb complicates disorders related to the hypothalamus, including those that cause structural damage to the hypothalamus, pituitary macroadenoma with suprasellar extension, glioma, meningioma, teratoma, germ cell tumors, radiotherapy, Bj syndrome, and mutations in leptin, leptin receptor, POMC, MC4R and CART genes. Related Topics. Other causes for hypothalamic obesity include other rare tumors, head trauma, swelling in the brain and being born with a brain malformation. Nutritional and lifestyle counseling can also help with weight management. Summary Summary. References 1 Garrow, J. The hypothalamus regulates body weight by precisely balancing the intake of food, energy expenditure and body fat tissue.

A list of causes of obesity can be found in the Table. You May Be Interested In. Harold Bays, now makes it a treatment goal to return adipose tissue function to normal.

Menu Search FindZebra Diagnosis Assist Tool. You May Be Interested In. Hypothalamic obesity in children. These include metforminoctreotideand GLP1 receptor agonists. Silver Spring14 3pp.

READ TOO: 1. Kosmische Geschwindigkeit Berechnung Bmi

The system is intended to complement current measures and has been found to be a strong, independent predictor of increasing mortality; however, it is still unclear how to best incorporate the system into clinical practice. Explains what nerves are affected in each type of diabetic neuropathy. One hypothesis is that people who are obese are resistant to endogenous leptin signaling. Am J Epidemiol. Exogenous ghrelin is associated with increased food intake, reduced resting energy expenditure, and catabolism in adipose tissue. The mean BMI of the pop-ulation was Obesity is associated with longterm negative economic consequences.

Sept ; 13 9 Definihion For individuals, BMI is screening tool, but it does not cdc body fatness or health. Finding Funding Opportunities. They can direct you to research, resources, and services. Substances Psychotropic Drugs. Corticotropin-releasing hormone, adrenocorticotropic hormone glucocorticoids and the 11beta-HSD-1 shuttle regulate lipolysis both directly and indirectly. There are a few rare genetic inherited conditions that include the symptoms of hypothalamic obesity such as Bardet-Biedl syndrome and leptin deficiency.

Chronodisruption Chronodisruption is associated with the development of obesity, prediabetes, diabetes, and lipid disorders. ICSI website. The polycystic ovary syndrome associat-ed with morbid obesity may resolve after weight loss induced by bariatric surgery. Caring for Your Patient with a Rare Disease. Use of this website is conditional upon your acceptance of our user agreement. Physiological factor in obesity.

Froelich's adiposity; Froelich's syndrome; Froehlich syndrome; Froelich's hyopthalamic Froelich's syndrome; Froehlich syndrome; Adiposogenital dystrophy; Babinski-Froelich syndrome; Adiposodysgenesis See More. There are a few rare genetic inherited conditions that include the symptoms of hypothalamic obesity such as Bardet-Biedl syndrome and leptin deficiency. The in-depth resources contain medical and scientific language that may be hard to understand.

Valproic acid, carbamazepine, and gabapentin are antiepileptic medications that are associated with weight gain. Public Health Rep. Tips for the Undiagnosed. The role of obesity measures in the development and persistence of major depressive disorder. Antidepressants Common treatments of MDD may increase the risk of obesity. The goal of treatment in general is to promote weight loss and control hunger.

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Sept ; 13 9 How to Find a Disease Specialist. Nutritional and lifestyle counseling can also help with weight management. Abstract Following extensive suprasellar operations for excision of hypothalamic tumors, some patients develop morbid obesity, the so-called hypothalamic obesity HyOb. J Pediatr Endocrin Metab. The most important afferent signals deranged are energy regulation by the sympathetic nervous system and regulation of insulin secretion.

Cdc to deffinition non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. The pathophysiology includes loss of sensitivity to afferent peripheral humoral signals, such as, leptin on the one hand and dysfunctional afferent signals, on the other hand. If you do not want your question posted, please let us know. Abstract Hypothalamic obesity HyOb was first defined as the significant polyphagia and weight gain that occurs after extensive suprasellar operations for excision of hypothalamic tumours. References References. Related Topics. Substances Psychotropic Drugs.

Polypharmacy, either adding a second antidepressant or an atypical antipsychotic, may become necessary for the management of MDD. Finding Funding Opportunities. A review of the prevalence and economic consequences of obesity is provided. Genetic influences on BMI appear to be strongly correlated.

Updated September 9, Relation between con-sumption of sugar-sweetened drinks and childhood obesity: a pro-spective, observational analysis. The chronobiology, etiology and pathophysiology of obesity. Home » Endocrine Disorders » Obesity. Thyroid Cancer Guide A neck lump or nodule is the most common symptom of thyroid cancer.

Weight that is higher than what is considered healthy for a given height is described as overweight or obesity. Most people with this condition are treated with a combination of gastric surgery, medications, and nutritional and lifestyle counseling. Obes Rev. References References.

Comparison of dual-energy x-ray absorptiometric and anthropometric measures of adiposity in relation to adiposity-related biologic factors. References 1 Garrow, J. Other medications include stimulants and hormonal treatments. Links with this icon indicate that you are leaving the CDC website. Other causes for hypothalamic obesity include other rare tumors, head trauma, swelling in the brain and being born with a brain malformation. Treatment Treatment.

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